Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(3-nitrophenyl)ethyl]-, (R*,R*)- (9CI)
CAS: 138125-72-1
Molecular Formula: C11H12Cl2N2O5
Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(3-nitrophenyl)ethyl]-, (R*,R*)- (9CI) - Names and Identifiers
| Synonyms | 2,2-dichloro-N-[(1S,2S)-1,3-dihydroxy-1-(3-nitrophenyl)propan-2-yl]acetamide Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(3-nitrophenyl)ethyl]-, (R*,R*)- (9CI) |
| CAS | 138125-72-1 |
Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(3-nitrophenyl)ethyl]-, (R*,R*)- (9CI) - Physico-chemical Properties
| Molecular Formula | C11H12Cl2N2O5 |
| Molar Mass | 323.13 |
| Storage Condition | 2-8℃ |
Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(3-nitrophenyl)ethyl]-, (R*,R*)- (9CI) - Introduction
Chloramphenicol is a broad-spectrum antibiotic, also known as chloramphenicol threo. The following is a description of its nature, use, preparation and safety information:
Nature:
m-Chloramphenicol is a white to slightly yellow crystalline powder with a faint chloromycetin odor. It is practically insoluble in water and soluble in alcohols, ethers and organic solvents. In addition, it is a powerful antibacterial drug that can inhibit the growth and reproduction of bacteria.
Use:
m-Chloramphenicol is widely used in the field of medicine. It can treat a variety of infectious diseases, including respiratory tract, genitourinary system, eyes, gastrointestinal tract and other parts of the infection. In addition, m-chloramphenicol can also be used in the aquaculture industry as a feed additive to prevent and treat infectious diseases in animals.
Method:
The preparation method of m-chloramphenicol is mainly produced by microbial fermentation. First, yellow mold (Streptomyces aureofaciens) was selected as the fermentation strain. Then, the strain is inoculated into a medium and cultured under appropriate culture conditions. When the strain grows and multiplies in the medium, it will synthesize chloramphenicol m. Finally, pure chloramphenicol was obtained by extraction, purification and other steps.
Safety Information:
Chloramphenicol is a relatively safe drug when used correctly. However, excessive use or long-term use may lead to some adverse reactions, such as allergies, liver toxicity, blood system abnormalities. In addition, for pregnant women, lactating women and patients with liver and kidney dysfunction, it should be used with caution. When using M-chloramphenicol, it should be used correctly according to the guidance and advice of doctors, and the relevant safety measures should be observed.
Nature:
m-Chloramphenicol is a white to slightly yellow crystalline powder with a faint chloromycetin odor. It is practically insoluble in water and soluble in alcohols, ethers and organic solvents. In addition, it is a powerful antibacterial drug that can inhibit the growth and reproduction of bacteria.
Use:
m-Chloramphenicol is widely used in the field of medicine. It can treat a variety of infectious diseases, including respiratory tract, genitourinary system, eyes, gastrointestinal tract and other parts of the infection. In addition, m-chloramphenicol can also be used in the aquaculture industry as a feed additive to prevent and treat infectious diseases in animals.
Method:
The preparation method of m-chloramphenicol is mainly produced by microbial fermentation. First, yellow mold (Streptomyces aureofaciens) was selected as the fermentation strain. Then, the strain is inoculated into a medium and cultured under appropriate culture conditions. When the strain grows and multiplies in the medium, it will synthesize chloramphenicol m. Finally, pure chloramphenicol was obtained by extraction, purification and other steps.
Safety Information:
Chloramphenicol is a relatively safe drug when used correctly. However, excessive use or long-term use may lead to some adverse reactions, such as allergies, liver toxicity, blood system abnormalities. In addition, for pregnant women, lactating women and patients with liver and kidney dysfunction, it should be used with caution. When using M-chloramphenicol, it should be used correctly according to the guidance and advice of doctors, and the relevant safety measures should be observed.
Last Update：2024-04-09 21:01:54
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